On October 16, 2009, at the young age of 2 1/2 years old, Wren passed away at Gillette Children's Hospital in St. Paul, MN.
Friends and family followed Wren's story on the Caringbridge website, after she suffered a head injury at daycare. Wren was hurt on October 9, 2009. She was quickly flown to Regions Hospital where doctors removed a blood clot by Wren's brain. Later, Wren was transferred to Gillette Children's Hospital, where she remained in a week long coma.
Wren's family wants to keep her memory alive with an annual Wren Sprague Memorial Run/Walk. The proceeds of the Run/Walk are donated to the PICU at Gillette Children's Hospital.
The Wren Sprague Memorial & Scholarship fund also awards two annual scholarships to local high school seniors, who are pursuing careers in the medical field.